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Type of Document Dissertation Author Xiang, Xiaorong Author's Email Address xxiang1@nd.edu URN etd-04202007-133530 Title Service-oriented architecture for integration of bioinformatic data and applications Degree Doctor of Philosophy Department Computer Science and Engineering Advisory Committee
Advisor Name Title Frank Collins Committee Chair Aaron Striegel Committee Member Jeanne Romero-Severson Committee Member Patrick J. Flynn Committee Member Keywords
- service-oriented architecture
- web services
- semantic web
- bioinformatic data and applications integration
- scientific workflow
- service composition
Date of Defense 2007-04-05 Availability unrestricted Abstract Service oriented architecture (SOA) is a new paradigm that originated in industry for future distributed computing. It is recognized as a promising architecture for application integration inside and across organizations. Since their introduction, semantic web and web services technologies are increasingly gaining interest in the implementation of e-Science infrastructures. In this dissertation, we survey current research trends and challenges for adopting SOA in general. We present a practical experiment of building a service-oriented system for data integration and analysis using current web services technologies and bioinformatics middleware. The system is enhanced with an ontological model for semantics annotation of services and data. It demonstrates that adopting SOA in the e-Science field can accelerate the scientific research process. A new methodology and an enhanced system design is proposed to facilitate the reuse of workflows and verified knowledge.
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